The museum houses exhibits of Archaic, Classical, Hellenistic and Roman sculptures from the city of Thessaloniki in particular and the Macedonia region in general. One wing hosts the finds from the Sindos cemetery and is called 'The Gold of Macedon'.

Thessaloniki Museum is located in the heart of Thessaloniki, Greece. It is one of the most popular museums in the city and is home to a wide variety of artwork from various time periods. The museum was founded in 1973 and is housed in a renovated Ottoman-style mansion. It consists of seven permanent collections and one temporary collection, covering a range of topics from Byzantine art and Greek folk art to classical sculpture and modern art. The museum’s collections feature over 4,000 artifacts, including paintings, sculptures, photographs, pottery, and coins.

The Byzantine Art Collection includes icons, frescoes, and other religious artifacts from the Byzantine era. The Greek Folk Art Collection features items from the 19th and 20th centuries, such as traditional costumes, musical instruments, and other artifacts of daily life. The Classical Sculpture Collection includes ancient statues and busts from the Archaic, Classical, and Hellenistic periods. The Modern Art Collection features works from the 19th and 20th centuries, including paintings and sculptures by prominent Greek modernists. The museum also offers a range of educational programs, such as lectures, workshops, and guided tours.