The Plantin-Moretus Museum is a printing plant and publishing house dating from the Renaissance and Baroque periods. Situated in Antwerp, one of the three leading cities of early European printing along with Paris and Venice, it is associated with the history of the invention and spread of typography. Its name refers to the greatest printer-publisher of the second half of the 16th century: Christophe Plantin (c. 1520–89). The monument is of outstanding architectural value. It contains exhaustive evidence of the life and work of what was the most prolific printing and publishing house in Europe in the late 16th century. The building of the company, which remained in activity until 1867, contains a large collection of old printing equipment, an extensive library, invaluable archives and works of art, among them a painting by Rubens.Through the publications of the Officina Plantiniana, the Plantin-Moretus complex is a testimony to the major role played by this important centre of 16th century European humanism in the development of science and culture.